Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD6 | Q9BV23 | 5/20 | 0.52 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 7/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15029231 | 0.84 | TRAP1 (0.49) | TRAP1TAS1R3TAS1R1TAS1R2NOTUM | |
| SCHEMBL4437645 | 0.80 | ABHD6 (0.57) | ABHD6TRAP1NOTUMCARM1PRMT6 | |
| SCHEMBL7602212 | 0.79 | NOTUM (0.61) | TAS1R3TAS1R1TAS1R2NOTUMNAMPT | |
| SCHEMBL16101789 | 0.75 | ABHD6 (0.52) | ABHD6TRAP1NOTUM | |
| SCHEMBL29421757 | 0.75 | ABHD6 (0.62) | ABHD6TRAP1NAMPT | |
| SCHEMBL3578620 | 0.75 | ABHD6 (0.62) | ABHD6TRAP1NAMPT | |
| SCHEMBL12164470 | 0.73 | ABHD6 (0.67) | ABHD6TRAP1NOTUMCARM1PRMT6 | |
| SCHEMBL17887847 | 0.72 | ABHD6 (0.49) | ABHD6TRAP1NOTUMCARM1PRMT6 | |
| SCHEMBL31070514 | 0.72 | TRPV1 (0.49) | ABHD6TRAP1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL12269322 | 0.72 | NOTUM (0.61) | ABHD6TRAP1NOTUMCARM1BAZ2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735422-A1 | SUBSTITUTED CYCLIC COMPOUNDS AND METHODS OF TREATING PHENYLKETONURIA AND OTHER AMINO ACIDURIAS | Sanofi (FR) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025006827-A1 | SUBSTITUTED CYCLIC COMPOUNDS AND METHODS OF TREATING PHENYLKETONURIA AND OTHER AMINO ACIDURIAS | GENZYME CORPORATION (US) | 2025-01-02 | — | — | WO | disclosed |