Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRAP1 | Q12931 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 7/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.46 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31414516 | 0.84 | ABHD6 (0.52) | TRAP1NAMPTTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7602212 | 0.82 | NOTUM (0.61) | NAMPTTAS1R3TAS1R1TAS1R2NOTUM | |
| SCHEMBL7946982 | 0.81 | TRAP1 (0.52) | TRAP1NAMPTTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL27908431 | 0.79 | TRAP1 (0.51) | TRAP1NAMPTTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL21476810 | 0.77 | SMN1; SMN2 (0.55) | TRAP1NAMPTTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL3634459 | 0.77 | RAB9A (0.67) | NAMPTTAS1R3TAS1R1TAS1R2NPC1 | |
| SCHEMBL18376168 | 0.77 | TRAP1 (0.49) | TRAP1NPC1RAB9ASMN1; SMN2NOTUM | |
| SCHEMBL13473657 | 0.77 | RIPK1 (0.53) | TRAP1NPC1RAB9ASMN1; SMN2NOTUM | |
| SCHEMBL5319230 | 0.76 | TAS1R3 (0.52) | TRAP1NAMPTTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL5923951 | 0.75 | TAS1R3 (0.61) | TAS1R3TAS1R1TAS1R2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130149281-A1 | ORGANIC COMPOUNDS AND THEIR USES | NOVARTIS AG (CH) | 2013-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130149281-A1 | ORGANIC COMPOUNDS AND THEIR USES | OAT, HAVCR2, CPT1A | TRAP1 2345/4885NAMPT 1563/4885TAS1R3 3709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.