Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 7/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CBLB | Q13191 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31512011 | 0.79 | MTOR (0.38) | TYK2PIK3CA | |
| SCHEMBL31415394 | 0.78 | PLA2G7 (0.40) | TSHRGAAKDM4ENSD2ALDH1A1 | |
| SCHEMBL31415449 | 0.78 | PDE3B (0.32) | TSHRGLAPOLBGAANTRK1 | |
| SCHEMBL31463510 | 0.78 | SCN9A (0.41) | TSHRGLAPOLBGAAKDM4E | |
| SCHEMBL31415439 | 0.77 | PLA2G7 (0.39) | TSHRKDM4ENSD2ALDH1A1MAPT | |
| SCHEMBL31415385 | 0.76 | KEAP1 (0.49) | TSHRGLAPOLBGAANTRK1 | |
| SCHEMBL31512055 | 0.73 | PIK3R1 (0.37) | CYP1A2TYK2PIK3CA | |
| SCHEMBL31415375 | 0.73 | DRD2 (0.37) | KDM4ENSD2ALDH1A1MAPTTYK2 | |
| SCHEMBL2808894 | 0.73 | TSHR (0.67) | TSHRGLAPOLBGAANR1H2 | |
| SCHEMBL31231632 | 0.72 | GAA (0.47) | TSHRGLAPOLBGAANR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054368-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | NICO THERAPEUTICS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |