Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 18/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31415371 | 0.79 | GLA (0.42) | NTRK1GLAPOLBGAATSHR | |
| SCHEMBL17130017 | 0.79 | NTRK1 (0.63) | NTRK1 | |
| SCHEMBL31415329 | 0.77 | KEAP1 (0.55) | KEAP1TSHR | |
| SCHEMBL9383781 | 0.77 | HSD11B1 (0.54) | NTRK1 | |
| SCHEMBL17110550 | 0.77 | NTRK1 (0.62) | NTRK1 | |
| SCHEMBL29633248 | 0.77 | NTRK1 (0.62) | NTRK1 | |
| SCHEMBL31415453 | 0.76 | TSHR (0.42) | NTRK1GLAPOLBGAATSHR | |
| SCHEMBL17111096 | 0.76 | NTRK1 (0.59) | NTRK1 | |
| SCHEMBL31415382 | 0.76 | KEAP1 (0.53) | KEAP1 | |
| SCHEMBL31241561 | 0.76 | KEAP1 (0.53) | KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054368-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | NICO THERAPEUTICS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |