Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.36 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31415289 | 0.93 | KEAP1 (0.44) | KEAP1ALOX5APFEN1JMJD6DRD2 | |
| SCHEMBL31415538 | 0.82 | KEAP1 (0.45) | KEAP1JMJD6DRD2BMPR1AACVRL1 | |
| SCHEMBL31512068 | 0.79 | ALOX5AP (0.43) | KEAP1ALOX5APFEN1JMJD6DRD2 | |
| SCHEMBL31415235 | 0.79 | CHRM2 (0.36) | ALOX5APFEN1DRD2HTR1DHTR1B | |
| SCHEMBL31415375 | 0.78 | DRD2 (0.37) | DRD2HTR1DHTR1BKDM4ENSD2 | |
| SCHEMBL31415329 | 0.76 | KEAP1 (0.55) | KEAP1KMT2AKDM4ENSD2ALDH1A1 | |
| SCHEMBL31415382 | 0.74 | KEAP1 (0.53) | KEAP1JMJD6KMT2AKDM4ENSD2 | |
| SCHEMBL31512085 | 0.74 | JMJD6 (0.38) | ALOX5APFEN1JMJD6DRD2BMPR1A | |
| SCHEMBL31415414 | 0.72 | KEAP1 (0.50) | KEAP1JMJD6KMT2AKDM4ENSD2 | |
| SCHEMBL31241561 | 0.71 | KEAP1 (0.53) | KEAP1ALOX5APFEN1JMJD6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054368-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | NICO THERAPEUTICS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |