Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.59 |
| ▸ | PIK3CG | P48736 | 13/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 12/20 | 0.48 |
| ▸ | MTOR | P42345 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 10/20 | 0.41 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5218113 | 0.87 | ACHE (0.71) | ACHEPIK3CGPIK3CDMTORMAPT | |
| SCHEMBL21939240 | 0.86 | ACHE (0.59) | ACHEPIK3CGPIK3CDMTORKDM4E | |
| SCHEMBL16481865 | 0.82 | RAB9A (0.46) | ACHEPIK3CGPIK3CDMTORKDM4E | |
| SCHEMBL21939273 | 0.80 | ACHE (0.56) | ACHEPIK3CGPIK3CDMTORRAB9A | |
| SCHEMBL31415598 | 0.80 | RAB9A (0.42) | ACHEPIK3CGPIK3CDMTORKDM4E | |
| SCHEMBL12909247 | 0.79 | ACHE (0.46) | ACHEPIK3CGPIK3CDMTORMAPT | |
| SCHEMBL964682 | 0.78 | ACHE (0.53) | ACHEKDM4EMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL16481829 | 0.77 | NR1H4 (0.48) | ACHEPIK3CGPIK3CDMTORKDM4E | |
| SCHEMBL31415531 | 0.76 | ALDH1A1 (0.47) | ACHEKDM4EMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL981283 | 0.74 | ACHE (1.00) | ACHEKDM4EMAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054368-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | NICO THERAPEUTICS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |