Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 2/20 | 0.37 |
| ▸ | CDK4 | P11802 | 2/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.37 |
| ▸ | CCND1 | P24385 | 2/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | CCND3 | P30281 | 2/20 | 0.37 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | PI4KA | P42356 | 2/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31416796 | 0.86 | LRRK2 (0.38) | LRRK2ALDH1A1CDK1CDK4CCNB1 | |
| SCHEMBL15182837 | 0.78 | PIK3CD (0.46) | ALDH1A1HSD17B10PIK3CDPIK3CBPIK3CG | |
| SCHEMBL369300 | 0.77 | L3MBTL1 (0.44) | ALDH1A1HSD17B10PIK3CDPIK3CBPIK3CG | |
| SCHEMBL31416730 | 0.74 | PIK3CD (0.45) | ALDH1A1HSD17B10PIK3CDPIK3CBPIK3CG | |
| SCHEMBL18282733 | 0.69 | ACHE (0.49) | LRRK2ALDH1A1BRD4CREBBPNR1I2 | |
| SCHEMBL330400 | 0.68 | ALDH1A1 (0.65) | ALDH1A1HSD17B10RORB | |
| SCHEMBL28734614 | 0.67 | LRRK2 (0.41) | LRRK2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL23570884 | 0.66 | HIF1A (0.50) | LRRK2ALDH1A1BRD4CREBBP | |
| SCHEMBL31341028 | 0.65 | PIM1 (0.35) | LRRK2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL19537429 | 0.64 | KDM5A (0.46) | LRRK2CDK1CDK4CCNB1CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746964-A1 | NEW PYRAZOLOPYRIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025017078-A1 | NEW PYRAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-23 | — | — | WO | disclosed |