Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31416784 | 0.84 | KCNH2 (0.34) | — | |
| SCHEMBL31416778 | 0.82 | FUCA1 (0.31) | MEN1KMT2A | |
| SCHEMBL31705681 | 0.70 | ESR1 (0.34) | MEN1TSHRKMT2A | |
| SCHEMBL31416843 | 0.68 | ALDH1A1 (0.43) | — | |
| SCHEMBL29743579 | 0.68 | SMN1; SMN2 (0.31) | TSHR | |
| SCHEMBL30212381 | 0.65 | GRIN2B (0.36) | — | |
| SCHEMBL30459603 | 0.61 | BPTF (0.48) | TSHR | |
| SCHEMBL31110042 | 0.60 | GLS (0.34) | — | |
| SCHEMBL21403160 | 0.60 | KDM4E (0.41) | TSHR | |
| SCHEMBL9957060 | 0.60 | TBXA2R (0.40) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746964-A1 | NEW PYRAZOLOPYRIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2026-05-27 | — | — | EP | disclosed |
| WO-2026046976-A1 | PYRAZOLOPYRIDINE PHOSPHATE ESTERS FOR MODULATING SALT-INDUCIBLE KINASE (SIK) | F. HOFFMANN-LA ROCHE AG (CH) | 2026-03-05 | — | — | WO | disclosed |
| WO-2025017078-A1 | NEW PYRAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-23 | — | — | WO | disclosed |