Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | VNN1 | O95497 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2729935 | 0.76 | ADRA2A (0.59) | ADRA2AADRA2BADRA2CPLAUGAA | |
| SCHEMBL31465345 | 0.73 | ALDH1A1 (0.38) | ESR1ESR2GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL28294254 | 0.72 | TBXA2R (0.42) | TBXA2RESR1ESR2ADRA2AADRA2B | |
| SCHEMBL2013760 | 0.72 | TBXA2R (0.52) | TBXA2RVNN1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL2013758 | 0.72 | TBXA2R (0.52) | TBXA2RVNN1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL30189924 | 0.72 | TBXA2R (0.42) | TBXA2RESR1ESR2ADRA2AADRA2B | |
| SCHEMBL30281198 | 0.72 | GFER (0.36) | ESR1ESR2PLAUSMN1; SMN2KMT2A | |
| SCHEMBL9950334 | 0.72 | GFER (0.36) | ESR1ESR2PLAUSMN1; SMN2KMT2A | |
| SCHEMBL1853792 | 0.69 | MAOA (0.41) | ALDH1A1CYP1A2GOT1DHODH | |
| SCHEMBL27983624 | 0.69 | GOT1 (0.41) | CYP1A2GOT1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116390917-A | MRGX2 antagonists | 葛兰素史密斯克莱知识产权发展有限公司 | 2023-07-04 | — | — | CN | disclosed |
| WO-2012088266-A2 | SUBSTITUTED IMIDAZOPYRIDAZINES AND BENZIMIDAZOLES AS INHIBITORS OF FGFR3 | INCYTE CORPORATION (US) | 2012-06-28 | — | — | WO | disclosed |