Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31416733 | 0.84 | MEN1 (0.30) | — | |
| SCHEMBL31416778 | 0.77 | FUCA1 (0.31) | — | |
| SCHEMBL31416731 | 0.74 | TLR8 (0.38) | KCNH2MCHR1 | |
| SCHEMBL31416849 | 0.71 | ALDH1A1 (0.40) | KCNH2MCHR1CYP2D6 | |
| SCHEMBL29743579 | 0.70 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL31416767 | 0.68 | CXCR4 (0.36) | KCNH2MCHR1CYP2D6 | |
| SCHEMBL31705681 | 0.67 | ESR1 (0.34) | CYP3A4CYP2D6 | |
| SCHEMBL24046712 | 0.65 | CYP11B1 (0.34) | KCNH2MCHR1 | |
| SCHEMBL30351050 | 0.65 | LMNA (0.37) | KCNH2MCHR1 | |
| SCHEMBL25746604 | 0.65 | LMNA (0.37) | KCNH2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746964-A1 | NEW PYRAZOLOPYRIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2026-05-27 | — | — | EP | disclosed |
| WO-2026046976-A1 | PYRAZOLOPYRIDINE PHOSPHATE ESTERS FOR MODULATING SALT-INDUCIBLE KINASE (SIK) | F. HOFFMANN-LA ROCHE AG (CH) | 2026-03-05 | — | — | WO | disclosed |
| WO-2025017078-A1 | NEW PYRAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-23 | — | — | WO | disclosed |