SCHEMBL31416786

SCHEMBL31416786

CC1(C)OB(c2cnn3cc(O)ccc23)OC1(C)C

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.38
UCHL1 P09936 1/20 0.36
IRAK4 Q9NWZ3 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27075947 0.83 IRAK4 (0.37) FFAR1UCHL1IRAK4
SCHEMBL1693695 0.82 LPL (0.41) FFAR1UCHL1IRAK4
SCHEMBL31416827 0.82 FFAR1 (0.35) FFAR1UCHL1IRAK4
SCHEMBL24369880 0.82 EPHB3 (0.36) FFAR1UCHL1IRAK4
SCHEMBL31416830 0.79 UCHL1 (0.46) FFAR1UCHL1IRAK4
SCHEMBL25417163 0.77 PIK3CG (0.40)
SCHEMBL1356211 0.77 DRD3 (0.40) UCHL1IRAK4
SCHEMBL23631039 0.76 UCHL1 (0.33) FFAR1UCHL1IRAK4
SCHEMBL31416769 0.74 DGAT1 (0.52) UCHL1
SCHEMBL30926273 0.74 ROCK2 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4746964-A1 NEW PYRAZOLOPYRIDINE DERIVATIVES F. Hoffmann-La Roche AG (CH) 2026-05-27 EP disclosed
WO-2026046976-A1 PYRAZOLOPYRIDINE PHOSPHATE ESTERS FOR MODULATING SALT-INDUCIBLE KINASE (SIK) F. HOFFMANN-LA ROCHE AG (CH) 2026-03-05 WO disclosed
WO-2025017078-A1 NEW PYRAZOLOPYRIDINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2025-01-23 WO disclosed