SCHEMBL31419166

SCHEMBL31419166

Nc1nc(C(F)F)c(Br)s1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.37
MAPT P10636 1/20 0.37
ALOX15 P16050 1/20 0.37
ALOX12 P18054 1/20 0.37
KMT2A Q03164 1/20 0.37
HSD17B10 Q99714 1/20 0.37
NOS1 P29475 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13068462 0.67 ALDH1A1 (0.37) MAPTKMT2AHSD17B10
SCHEMBL330115 0.64 HSD17B10 (0.37) MEN1MAPTALOX15ALOX12KMT2A
SCHEMBL11663165 0.64
SCHEMBL20346770 0.59 SMN1; SMN2 (0.35) NOS1
SCHEMBL20144683 0.59 SMN1; SMN2 (0.31) NOS1
SCHEMBL11564617 0.58 CYP1A2 (0.46) MEN1MAPTALOX15ALOX12KMT2A
SCHEMBL2587218 0.58 MAPT (0.57) MEN1MAPTALOX15ALOX12KMT2A
SCHEMBL2873247 0.58 COPS5 (0.49) MEN1MAPTALOX15ALOX12KMT2A
SCHEMBL18898666 0.57 SMN1; SMN2 (0.37) MAPTHSD17B10NOS1
SCHEMBL6258086 0.56 NOS1 (0.52) MAPTHSD17B10NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4745134-A1 PROTEIN ARGINASE METHYLTRANSFERASE-5 INHIBITOR AND MEDICAL USE THEREOF Jiangsu Yahong Meditech Co., Ltd. (CN) 2026-05-20 EP disclosed
WO-2025016323-A1 PROTEIN ARGINASE METHYLTRANSFERASE-5 INHIBITOR AND MEDICAL USE THEREOF 江苏亚虹医药科技股份有限公司 2025-01-23 WO disclosed