Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 2/20 | 0.58 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.58 |
| ▸ | PRKCI | P41743 | 6/20 | 0.56 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.54 |
| ▸ | CDK1 | P06493 | 1/20 | 0.54 |
| ▸ | CDK4 | P11802 | 1/20 | 0.54 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.54 |
| ▸ | CCND1 | P24385 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | CCND3 | P30281 | 1/20 | 0.54 |
| ▸ | IKBKB | O14920 | 4/20 | 0.52 |
| ▸ | CHUK | O15111 | 4/20 | 0.52 |
| ▸ | JAK2 | O60674 | 4/20 | 0.52 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.52 |
| ▸ | JAK3 | P52333 | 2/20 | 0.52 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.52 |
| ▸ | PAK4 | O96013 | 1/20 | 0.52 |
| ▸ | CSF1R | P07333 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14020099 | 1.00 | CCNK (0.58) | CCNKCDK12PRKCICHEK1CDK1 | |
| SCHEMBL4748259 | 0.92 | CCNK (0.62) | CCNKCDK12PRKCICHEK1CDK1 | |
| SCHEMBL4751329 | 0.81 | TLR8 (0.57) | CCNKCDK12CHEK1JAK2JAK3 | |
| SCHEMBL31240621 | 0.80 | JAK2 (0.50) | PRKCICDK1CDK2CHUKJAK2 | |
| SCHEMBL31240700 | 0.80 | CLK2 (0.58) | JAK2JAK3CLK2DYRK1AJAK1 | |
| SCHEMBL4540461 | 0.80 | DYRK1B (0.55) | CCNA2CDK2JAK2JAK3DAPK3 | |
| SCHEMBL26686361 | 0.79 | IKBKB (0.51) | CDK1CDK2IKBKBCHUKJAK2 | |
| SCHEMBL26888731 | 0.79 | CLK2 (0.51) | CDK1CDK2JAK2AURKBJAK3 | |
| SCHEMBL31240519 | 0.78 | TBK1 (0.51) | PRKCIJAK2JAK3CLK2DYRK1A | |
| SCHEMBL30633279 | 0.78 | NUDT1 (0.52) | CCNKCDK12PRKCIIKBKBCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119562945-A | IKK inhibitors | 癌症研究技术有限公司 | 2025-03-04 | — | — | CN | claimed |
| CN-119562945-A | IKK inhibitors | 癌症研究技术有限公司 | 2025-03-04 | — | — | CN | disclosed |