Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.58 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | CRACR2A | Q9BSW2 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21879588 | 0.85 | KLKB1 (0.62) | PTGS2KLKB1PTGS1MAPTCYP2C9 | |
| SCHEMBL31420334 | 0.85 | KLKB1 (0.62) | PTGS2KLKB1PTGS1MAPTCYP2C9 | |
| SCHEMBL537395 | 0.84 | PTGS1 (0.65) | PTGS2KLKB1PTGS1MAPTPDPK1 | |
| SCHEMBL25249559 | 0.84 | PTGS2 (0.57) | PTGS2KLKB1PTGS1HDAC3HDAC4 | |
| SCHEMBL4053403 | 0.84 | PTGS2 (0.60) | PTGS2KLKB1PTGS1HDAC3HDAC4 | |
| SCHEMBL4247328 | 0.83 | PTGS2 (0.74) | PTGS2PTGS1HDAC3HDAC4HDAC1 | |
| SCHEMBL25251421 | 0.83 | THRB (0.48) | PTGS2PTGS1HDAC3HDAC4HDAC1 | |
| SCHEMBL7330567 | 0.82 | PTGS1 (0.63) | PTGS2KLKB1PTGS1MAPTPDPK1 | |
| SCHEMBL538151 | 0.81 | PTGS2 (0.51) | PTGS2PTGS1HDAC3HDAC4HDAC1 | |
| SCHEMBL31255079 | 0.80 | PTGS2 (0.54) | PTGS2KLKB1PTGS1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059469-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS AS AKT INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |