SCHEMBL3142111

SCHEMBL3142111

CC1Cc2ccccc2C(C)N1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 3/20 0.49
GRIN2D O15399 1/20 0.47
GRIN3B O60391 1/20 0.47
GRIN1 Q05586 1/20 0.47
GRIN2A Q12879 1/20 0.47
GRIN2B Q13224 1/20 0.47
GRIN2C Q14957 1/20 0.47
GRIN3A Q8TCU5 1/20 0.47
TSHR P16473 1/20 0.43
CHRNB2 P17787 1/20 0.41
CHRNA4 P43681 1/20 0.41
HTR2A P28223 1/20 0.39
HTR2C P28335 1/20 0.39
HTR2B P41595 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29711708 1.00 OPRM1 (0.49) OPRM1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL16982797 1.00 OPRM1 (0.49) OPRM1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL18685556 1.00 OPRM1 (0.49) OPRM1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL8830231 0.80 OPRM1 (0.46) OPRM1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL21767243 0.80 TSHR (0.50) OPRM1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL1010444 0.77 OPRM1 (0.44) OPRM1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL10481209 0.77 OPRM1 (0.44) OPRM1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL11821224 0.76 OPRM1 (0.42) OPRM1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL24110693 0.75 TRPM5 (0.43) CHRNB2CHRNA4HTR2AHTR2CHTR2B
SCHEMBL8722537 0.74 MAPT (0.51) OPRM1GRIN2DGRIN3BGRIN1GRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025101780-A1 PHARMACOLOGICAL CORRECTORS OF RHODOPSIN AND USES THEREOF OCTANT, INC. (US) 2025-05-15 WO disclosed
US-7642344-B2 Methods and compositions for determining the sequence of nucleic acid molecules OPERON BIOTECHNOLOGIES, INC. (US) 2010-01-05 US disclosed
EP-0962537-B1 Methods for analyzing nucleic acid molecules utilizing sizing techniques OPERON BIOTECHNOLOGIES INC (US) 2009-06-17 EP disclosed
EP-0992511-B1 Methods and compositions for determining the sequence of nucleic acid molecules OPERON BIOTECHNOLOGIES INC (US) 2009-03-11 EP disclosed
US-20080009613-A1 Methods and compositions for determining the sequence of nucleic acid molecules OPERON BIOTECHNOLOGIES, INC. (US) 2008-01-10 US disclosed
US-7247434-B2 Methods and compositions for determining the sequence of nucleic acid molecules OPERON BIOTECHNOLOGIES, INC. (US) 2007-07-24 US disclosed
EP-0868535-B9 METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES QIAGEN GENOMICS INC (US) 2007-05-09 EP disclosed
US-7052846-B2 Methods and compositions for analyzing nucleic acid molecules utilizing sizing techniques OPERON BIOTECHNOLOGIES, INC. (US) 2006-05-30 US disclosed
US-20060057566-A1 METHODS AND COMPOSITIONS FOR ANALYZING NUCLEIC ACID MOLECULES UTILIZING SIZING TECHNIQUES QIAGEN GENOMICS, INC. (US) 2006-03-16 US disclosed
EP-0868535-B2 METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES QIAGEN GENOMICS INC (US) 2006-01-04 EP disclosed
EP-0962537-A2 Methods and compositions for analyzing nucleic acid molecules utilizing sizing techniques Rapigene, Inc. (US) 1999-12-08 EP disclosed
WO-1999005319-A9 METHODS AND COMPOUNDS FOR ANALYZING NUCLEIC ACIDS BY MASS SPECTROMETRY RAPIGENE INC (US) 1999-06-17 WO disclosed
WO-1999005319-A2 METHODS AND COMPOUNDS FOR ANALYZING NUCLEIC ACIDS BY MASS SPECTROMETRY RAPIGENE, INC. (US) 1999-02-04 WO disclosed
EP-0868535-A2 METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES Rapigene, Inc. (US) 1998-10-07 EP disclosed
EP-0840804-A1 METHODS AND COMPOSITIONS FOR ANALYZING NUCLEIC ACID MOLECULES UTILIZING SIZING TECHNIQUES DARWIN MOLECULAR CORPORATION (US) 1998-05-13 EP disclosed
WO-1997027331-A9 METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES 1997-10-09 WO disclosed
US-5670526-A ANTIINFLAMMATORY AGENT, IMMUNOSUPPRESSANT OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-09-23 US disclosed
WO-1997027331-A2 METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES RAPIGENE, INC. (US) 1997-07-31 WO disclosed
WO-1997027325-A2 METHODS AND COMPOSITIONS FOR ANALYZING NUCLEIC ACID MOLECULES UTILIZING SIZING TECHNIQUES RAPIGENE, INC. (US) 1997-07-31 WO disclosed
US-4846880-A 2-(Dichloroacetyl)-3-substituted-1,2,3,4-tetrahydroisoquinolines as herbicide antidotes MONSANTO COMPANY (US) 1989-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080009613-A1 Methods and compositions for determining the sequence of nucleic acid molecules CPSF6, RNMT, POLM OPRM1 1617/4885GRIN2D 4843/4885GRIN3B 4294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.