Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31421000 | 0.99 | TDP1 (0.38) | LMNAALDH1A1TDP1CYP3A4CYP2C19 | |
| SCHEMBL31420789 | 0.98 | LMNA (0.39) | LMNAALDH1A1TDP1CYP3A4CYP2C19 | |
| SCHEMBL31421302 | 0.94 | ALDH1A1 (0.40) | LMNAALDH1A1CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL31420897 | 0.93 | LMNA (0.41) | LMNAALDH1A1CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL31420569 | 0.91 | LMNA (0.42) | LMNAALDH1A1CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL31420613 | 0.90 | LMNA (0.38) | LMNAALDH1A1CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL31421049 | 0.90 | LMNA (0.38) | LMNAALDH1A1CYP3A4CYP2C19ABCB1 | |
| SCHEMBL31420654 | 0.90 | LMNA (0.39) | LMNAALDH1A1CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL31420930 | 0.90 | GHSR (0.36) | LMNAALDH1A1CYP3A4CYP2C19ABCB1 | |
| SCHEMBL31421424 | 0.90 | LMNA (0.42) | LMNAALDH1A1CYP3A4CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129021-A1 | SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS | Interdict Bio, Inc. (US) | 2025-04-24 | — | — | US | disclosed |
| WO-2025064718-A1 | SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS | Interdict Bio, Inc. (US) | 2025-03-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250129021-A1 | SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS | MYC, KRAS, NRAS | LMNA 3037/4885ALDH1A1 2630/4885TDP1 3388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.