SCHEMBL31421352

SCHEMBL31421352

CNC(=O)O[C@@H]1[C@@H](O)CN[C@@H]1Cc1ccc(-c2cn(-c3cc4ccc(O)cc4oc3=O)nn2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ADRA1A P35348 1/20 0.36
▸ CYP2D6 P10635 3/20 0.36
▸ SMN1; SMN2 Q16637 3/20 0.36
▸ MEN1 O00255 2/20 0.36
▸ KMT2A Q03164 2/20 0.36
▸ PI4KB Q9UBF8 1/20 0.36
▸ LMNA P02545 1/20 0.36
▸ MAPK1 P28482 1/20 0.36
▸ HIF1A Q16665 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ CYP2C9 P11712 1/20 0.36
▸ CYP2C19 P33261 1/20 0.36
▸ SLC2A1 P11166 1/20 0.36
▸ ESRRB O95718 1/20 0.35
▸ ESRRA P11474 1/20 0.35
▸ APP P05067 1/20 0.34
▸ GBA1 P04062 3/20 0.34
▸ GLA P06280 2/20 0.33
▸ AKR1B10 O60218 1/20 0.33
▸ AKR1B1 P15121 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32687713 0.88 ESRRB (0.37) ADRA1ACYP2D6SMN1; SMN2MEN1KMT2A
SCHEMBL32687362 0.85 ESRRB (0.35) ADRA1ACYP2D6SMN1; SMN2MEN1KMT2A
SCHEMBL31420646 0.83 CYP2D6 (0.45) ADRA1ACYP2D6SMN1; SMN2MEN1KMT2A
SCHEMBL31420878 0.78 PI4KB (0.34) ADRA1API4KBESRRBESRRAMIF
SCHEMBL13315789 0.72 MIF (0.56) ADRA1AMEN1KMT2AALDH1A1GLA
SCHEMBL13315792 0.72 CA12 (0.47) MEN1KMT2AESRRBESRRAGLA
SCHEMBL13315790 0.71 MIF (0.54) ALDH1A1MIF
SCHEMBL32687422 0.69 ESRRB (0.34) ADRA1API4KBESRRBESRRAAPP
SCHEMBL31377380 0.67 CYP2D6 (0.50) CYP2D6SMN1; SMN2MEN1KMT2ALMNA
SCHEMBL31421306 0.67 FLT3 (0.43) CYP2D6SMN1; SMN2MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-04-24 — — US disclosed
WO-2025064718-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS ADRA1A 4549/4885CYP2D6 2401/4885SMN1; SMN2 1576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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