SCHEMBL32687422

SCHEMBL32687422

CCO[C@@H]1[C@@H](OC(=O)OC(C)(C)C)CN(C(=O)OC(C)(C)C)[C@@H]1Cc1ccc(-c2cn(-c3cc4ccc(O)cc4oc3=O)nn2)cc1

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ ESRRB O95718 1/20 0.34
▸ ESRRA P11474 1/20 0.34
▸ ADRA1A P35348 1/20 0.33
▸ PI4KB Q9UBF8 1/20 0.33
▸ ABHD6 Q9BV23 1/20 0.32
▸ DAGLA Q9Y4D2 1/20 0.32
▸ MIF P14174 2/20 0.31
▸ PFKFB3 Q16875 1/20 0.31
▸ APP P05067 1/20 0.30
▸ S1PR1 P21453 2/20 0.30
▸ GRM5 P41594 1/20 0.30
▸ GRM1 Q13255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31420878 0.91 PI4KB (0.34) ESRRBESRRAADRA1API4KBABHD6
SCHEMBL32687054 0.89 ESRRB (0.33) ESRRBESRRAADRA1API4KBABHD6
SCHEMBL31421465 0.81 PI4KB (0.38) ESRRBESRRAADRA1API4KBMIF
SCHEMBL32687713 0.76 ESRRB (0.37) ESRRBESRRAADRA1API4KBMIF
SCHEMBL32687199 0.70 GPR119 (0.42) —
SCHEMBL13315792 0.69 CA12 (0.47) ESRRBESRRAS1PR1
SCHEMBL32687248 0.69 NR1H2 (0.33) —
SCHEMBL31421352 0.69 ADRA1A (0.36) ESRRBESRRAADRA1API4KBMIF
SCHEMBL32687362 0.69 ESRRB (0.35) ESRRBESRRAADRA1API4KBMIF
SCHEMBL13315790 0.69 MIF (0.54) MIF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2026-04-23 — — US disclosed
US-20260078116-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2026-03-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078116-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, MCL1 ESRRB 2577/4885ESRRA 2350/4885ADRA1A 4661/4885
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS KRAS, MYC, NRAS ESRRB 1078/4885ESRRA 806/4885ADRA1A 4201/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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