SCHEMBL32687713

SCHEMBL32687713

CCO[C@@H]1[C@@H](O)CN[C@@H]1Cc1ccc(-c2cn(-c3cc4ccc(O)cc4oc3=O)nn2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ESRRB O95718 1/20 0.37
▸ ESRRA P11474 1/20 0.37
▸ ADRA1A P35348 1/20 0.36
▸ MEN1 O00255 2/20 0.36
▸ KMT2A Q03164 2/20 0.36
▸ MIF P14174 2/20 0.35
▸ GBA1 P04062 3/20 0.35
▸ GLA P06280 2/20 0.35
▸ PI4KB Q9UBF8 1/20 0.35
▸ APP P05067 1/20 0.34
▸ PFKFB3 Q16875 1/20 0.34
▸ ALDH1A1 P00352 2/20 0.33
▸ KDM4E B2RXH2 1/20 0.33
▸ CYP2D6 P10635 3/20 0.33
▸ SMN1; SMN2 Q16637 3/20 0.33
▸ LMNA P02545 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ HIF1A Q16665 1/20 0.33
▸ CYP2C9 P11712 1/20 0.33
▸ CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32687362 0.91 ESRRB (0.35) ESRRBESRRAADRA1AMEN1KMT2A
SCHEMBL31421352 0.88 ADRA1A (0.36) ESRRBESRRAADRA1AMEN1KMT2A
SCHEMBL31420646 0.77 CYP2D6 (0.45) ESRRBESRRAADRA1AMEN1KMT2A
SCHEMBL32687422 0.76 ESRRB (0.34) ESRRBESRRAADRA1AMIFPI4KB
SCHEMBL13315792 0.76 CA12 (0.47) ESRRBESRRAMEN1KMT2AGLA
SCHEMBL13315789 0.75 MIF (0.56) ADRA1AMEN1KMT2AMIFGLA
SCHEMBL13315790 0.73 MIF (0.54) MIFALDH1A1
SCHEMBL32687276 0.67 CYP2D6 (0.42) MEN1KMT2AGBA1ALDH1A1CYP2D6
SCHEMBL19491276 0.66 ESRRB (0.47) ESRRBESRRAADRA1AMEN1KMT2A
SCHEMBL32687507 0.66 ERCC1 (0.40) MEN1KMT2AGBA1ALDH1A1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2026-04-23 — — US disclosed
US-20260078116-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2026-03-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078116-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, MCL1 ESRRB 2577/4885ESRRA 2350/4885ADRA1A 4661/4885
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS KRAS, MYC, NRAS ESRRB 1078/4885ESRRA 806/4885ADRA1A 4201/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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