SCHEMBL3142147

SCHEMBL3142147

CCCCCCCCc1ccc(-c2nccc3ccccc23)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.46
ALDH1A1 P00352 4/20 0.46
KDM4E B2RXH2 4/20 0.46
MAPT P10636 4/20 0.46
RAB9A P51151 4/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
HPGD P15428 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
USP2 O75604 1/20 0.46
GAA P10253 1/20 0.46
HSD11B1 P28845 1/20 0.46
CTSV O60911 1/20 0.44
CTSL P07711 1/20 0.44
GPR84 Q9NQS5 1/20 0.43
TSHR P16473 1/20 0.42
NPC1 O15118 3/20 0.41
CYP3A4 P08684 2/20 0.41
ESR1 P03372 2/20 0.41
ADRA2A P08913 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28746601 1.00 HSD17B10 (0.46) HSD17B10ALDH1A1KDM4EMAPTRAB9A
SCHEMBL3134468 1.00 HSD17B10 (0.46) HSD17B10ALDH1A1KDM4EMAPTRAB9A
SCHEMBL28095643 0.99 HSD17B10 (0.45) HSD17B10ALDH1A1KDM4EMAPTRAB9A
SCHEMBL30273419 0.99 HSD17B10 (0.45) HSD17B10ALDH1A1KDM4EMAPTRAB9A
SCHEMBL17600561 0.99 HSD17B10 (0.45) HSD17B10ALDH1A1KDM4EMAPTRAB9A
SCHEMBL27551421 0.99 HSD11B1 (0.47) HSD17B10ALDH1A1KDM4EMAPTRAB9A
SCHEMBL10460557 0.94 HSD11B1 (0.46) HSD17B10ALDH1A1KDM4EMAPTRAB9A
SCHEMBL13169298 0.90 ALDH1A1 (0.42) HSD17B10ALDH1A1KDM4EMAPTRAB9A
SCHEMBL3142406 0.88 PDE10A (0.48) HSD17B10ALDH1A1KDM4EMAPTRAB9A
Acetoacetic Acid SCHEMBL29708957 0.86 TRPV1 (0.40) ALDH1A1MAPTRAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1348711-B1 LUMINESCENT ELEMENT AND DISPLAY CANON KK (JP) 2018-06-13 EP disclosed
EP-1889891-B1 Luminescence device and display apparatus CANON KK (JP) 2017-11-22 EP disclosed
US-20150076478-A1 LUMINESCENCE DEVICE AND DISPLAY APPARATUS CANON KK (JP) 2015-03-19 US disclosed
US-8920943-B2 Luminescence device and display apparatus CANON KABUSHIKI KAISHA (JP) 2014-12-30 US disclosed
EP-1489111-B1 POLYMERIC COMPOUND AND ELECTROLUMINESCENT ELEMENT CANON KK (JP) 2010-12-29 EP disclosed
CN-1927896-B Polymer compound and electroluminescent element CANON KK 2010-05-12 CN disclosed
US-7687155-B2 Comprises iridium complexes, coordination compounds; red phosphorescence; high efficiency CANON KABUSHIKI KAISHA (JP) 2010-03-30 US disclosed
US-20090230860-A1 POLYMER COMPOUND AND ELECTROLUMINESCENT ELEMENT CANON KABUSHIKI KAISHA (JP) 2009-09-17 US disclosed
US-20090184634-A1 LUMINESCENCE DEVICE AND DISPLAY APPARATUS CANON KABUSHIKI KAISHA (JP) 2009-07-23 US disclosed
US-7544426-B2 Comprises iridium complexes, coordination compounds; red phosphorescence; high efficiency CANON KABUSHIKI KAISHA (JP) 2009-06-09 US disclosed
CN-1285601-C Light emitting device and display CANON KK (JP) 2006-11-22 CN disclosed
US-7108924-B2 An Ir, Pt, Pd, or Rh complex is bonded to a main chain of a polymer via a substituent for imparting a given distance therebetween such as an acrylated acetoacetate group. CANON KABUSHIKI KAISHA (JP) 2006-09-19 US disclosed
US-20060177694-A1 Comprises iridium complexes, coordination compounds; red phosphorescence; high efficiency CANON KABUSHIKI KAISHA (JP) 2006-08-10 US disclosed
CN-1781925-A Luminescence device and display apparatus CANON KK (JP) 2006-06-07 CN disclosed
CN-1643003-A Polymer compound and electroluminescent element CANON KK (JP) 2005-07-20 CN disclosed
EP-1489111-A1 POLYMERIC COMPOUND AND ELECTROLUMINESCENT ELEMENT CANON KABUSHIKI KAISHA (JP) 2004-12-22 EP disclosed
CN-1474826-A Light emitting device and display ������������ʽ���� 2004-02-11 CN disclosed
US-20030224208-A1 Polymer compound and electroluminescent element CANON KABUSHIKI KAISHA (JP) 2003-12-04 US disclosed
EP-1348711-A1 LUMINESCENT ELEMENT AND DISPLAY CANON KABUSHIKI KAISHA (JP) 2003-10-01 EP disclosed
US-20030068526-A1 Such as tetrakis(1-(5-heptyloxyphenyl)isoquinoline-C2,N) (pu-dichloro) iridium (III); for red luminescence; graphic arts CANON KABUSHIKI KAISHA (JP) 2003-04-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060177694-A1 Comprises iridium complexes, coordination compounds; red phosphorescence; high efficiency AP3M1, MLEC, MLX HSD17B10 4838/4885ALDH1A1 4094/4885KDM4E 3317/4885
US-20090184634-A1 LUMINESCENCE DEVICE AND DISPLAY APPARATUS SOD1, NLRP1, LUC7L2 HSD17B10 2535/4885ALDH1A1 120/4885KDM4E 4129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.