Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | CTSA | P10619 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | POLQ | O75417 | 1/20 | 0.30 |
| ▸ | MELK | Q14680 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3401283 | 1.00 | GRIN2B (0.32) | GRIN2BPDE10ACHEK1PIK3CDGPR119 | |
| SCHEMBL2413395 | 0.89 | CTSA (0.37) | PDE10ACHEK1PIK3CDGPR119CTSA | |
| SCHEMBL2413398 | 0.89 | CTSA (0.37) | PDE10ACHEK1PIK3CDGPR119CTSA | |
| SCHEMBL2142042 | 0.88 | XDH (0.43) | GPR119KCNH2CYP11B2CYP11B1XDH | |
| SCHEMBL2142044 | 0.88 | XDH (0.43) | GPR119KCNH2CYP11B2CYP11B1XDH | |
| SCHEMBL1972967 | 0.86 | NOS1 (0.31) | NOS1NOS2 | |
| SCHEMBL1972962 | 0.86 | NOS1 (0.31) | NOS1NOS2 | |
| SCHEMBL2141868 | 0.86 | CYP11B2 (0.39) | CYP11B2CYP11B1CYP1A2MAOB | |
| SCHEMBL2141442 | 0.86 | CYP11B2 (0.39) | CYP11B2CYP11B1CYP1A2MAOB | |
| SCHEMBL314680 | 0.86 | MELK (0.32) | PDE10ACHEK1PIK3CDGPR119BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093394-B2 | Derivatives of 5-thioxylopyranose and use of same for treatment | LABORATOIRES FOURNIER S.A. (FR) | 2012-01-10 | — | — | US | disclosed |
| EP-2066683-B1 | DERIVATIVES OF 5-THIOXYLOPYRANOSE AND USE OF SAME FOR TREATMENT | FOURNIER LAB SA (FR) | 2010-11-03 | — | — | EP | disclosed |
| US-20090182013-A1 | Derivatives of 5-Thioxylopyranose and Use of Same for Treatment | LABORATOIRES FOURNIER S.A. (FR) | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090182013-A1 | Derivatives of 5-Thioxylopyranose and Use of Same for Treatment | TPMT, PNPO, PPOX | GRIN2B 4833/4885PDE10A 1836/4885CHEK1 4839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.