Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 2/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.41 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.41 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 4/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31423008 | 0.82 | GRIK1 (0.41) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL31423009 | 0.79 | GRIA1 (0.37) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL31422840 | 0.73 | DAO (0.61) | KDM4EALDH1A1POLBGAA | |
| SCHEMBL31423165 | 0.73 | DAO (0.61) | KDM4EALDH1A1 | |
| SCHEMBL8959808 | 0.73 | EIF4A3 (0.57) | FGFR1FGFR2FGFR3EGLN1KDM4E | |
| SCHEMBL463637 | 0.72 | GRIA1 (0.54) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL31422983 | 0.71 | HRH4 (0.46) | FGFR1PARP1KDM4EALDH1A1POLB | |
| SCHEMBL8828102 | 0.70 | KDM4E (0.53) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL9232962 | 0.70 | EGLN1 (0.39) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL3711310 | 0.69 | HSD17B10 (0.38) | GRIA1GRIA2GRIA3GRIA4GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |