Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | RARA | P10276 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31422833 | 0.83 | KDM4E (0.32) | KDM4EALDH1A1GAAPOLB | |
| SCHEMBL8828102 | 0.79 | KDM4E (0.53) | KDM4EALDH1A1GAAPOLBHPGD | |
| SCHEMBL31423389 | 0.76 | KDM4E (0.43) | KDM4EALDH1A1GAAPOLBHPGD | |
| SCHEMBL31422747 | 0.76 | CNR2 (0.38) | KDM4EALDH1A1GAAPOLBHPGD | |
| SCHEMBL31423132 | 0.75 | KDM4E (0.44) | KDM4EALDH1A1GAAPOLBHPGD | |
| SCHEMBL31422992 | 0.74 | KDM4E (0.33) | KDM4EALDH1A1HPGDHSD17B10EIF4A3 | |
| SCHEMBL31422910 | 0.73 | KDM4E (0.42) | KDM4EALDH1A1GAAPOLBHPGD | |
| SCHEMBL31422970 | 0.73 | KDM4E (0.42) | KDM4EALDH1A1GAAPOLBHPGD | |
| SCHEMBL31273247 | 0.70 | EIF4A3 (0.68) | KDM4EALDH1A1GAAPOLBHPGD | |
| SCHEMBL9398264 | 0.69 | EGLN1 (0.45) | KDM4EALDH1A1GAAPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |