Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30529281 | 1.00 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2KDM4EHPGDSLC16A3 | |
| SCHEMBL30529282 | 0.85 | MAOB (0.46) | ALDH1A1SMN1; SMN2KDM4EHPGDSLC16A3 | |
| SCHEMBL25426199 | 0.85 | MAOB (0.46) | ALDH1A1SMN1; SMN2KDM4EHPGDSLC16A3 | |
| SCHEMBL31273615 | 0.84 | SLC16A3 (0.54) | ALDH1A1SMN1; SMN2KDM4EHPGDSLC16A3 | |
| SCHEMBL10330642 | 0.76 | DAO (0.63) | ALDH1A1SMN1; SMN2KDM4EHPGDHSD17B10 | |
| SCHEMBL31423115 | 0.76 | DAO (0.63) | ALDH1A1KDM4EHPGDHSD17B10CYP2C19 | |
| SCHEMBL31272773 | 0.76 | DAO (0.51) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL29609392 | 0.76 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL28590063 | 0.76 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL30475158 | 0.75 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2KDM4EHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348394-A1 | COMPOSITIONS AND METHODS FOR TREATING MUSCULAR DYSTROPHIES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-11-02 | — | — | US | disclosed |
| US-20230348394-A1 | COMPOSITIONS AND METHODS FOR TREATING MUSCULAR DYSTROPHIES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-11-02 | — | — | US | disclosed |
| CN-116472269-A | Compositions and methods for treating muscular dystrophy | 加利福尼亚大学董事会 | 2023-07-21 | — | — | CN | disclosed |
| EP-4211131-A1 | COMPOSITIONS AND METHODS FOR TREATING MUSCULAR DYSTROPHIES | The Regents of the University of California (US) | 2023-07-19 | — | — | EP | disclosed |
| WO-2022055926-A1 | COMPOSITIONS AND METHODS FOR TREATING MUSCULAR DYSTROPHIES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348394-A1 | COMPOSITIONS AND METHODS FOR TREATING MUSCULAR DYSTROPHIES | TNNC1, PYGM, GYS1 | ALDH1A1 3470/4885SMN1; SMN2 4/4885KDM4E 3268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.