Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 12/20 | 0.64 |
| ▸ | DDO | Q99489 | 5/20 | 0.64 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31422983 | 0.79 | HRH4 (0.46) | DAODDOHRH4KDM4ESMN1; SMN2 | |
| SCHEMBL3362300 | 0.78 | DAO (1.00) | DAODDOHRH4 | |
| SCHEMBL3434396 | 0.76 | DAO (0.47) | DAODDOKDM4EALDH1A1KMT2A | |
| SCHEMBL15690441 | 0.75 | DAO (0.65) | DAODDOHRH4 | |
| SCHEMBL16767858 | 0.75 | DAO (1.00) | DAODDOHRH4 | |
| SCHEMBL16767856 | 0.75 | DAO (1.00) | DAODDOKDM4EALDH1A1LMNA | |
| SCHEMBL1145047 | 0.74 | HRH4 (0.60) | DAOHRH4KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL3359175 | 0.74 | DAO (0.64) | DAODDOKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL3419432 | 0.74 | DAO (0.51) | DAODDOKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL3432869 | 0.73 | DAO (0.58) | DAODDO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |