Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SCN4A | P35499 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20224935 | 0.82 | KIF11 (0.36) | NPC1RAB9AGMNNUSP2LMNA | |
| SCHEMBL21339745 | 0.82 | NPC1 (0.47) | NPC1RAB9AGMNNUSP2LMNA | |
| SCHEMBL2366206 | 0.80 | PDE2A (0.44) | NPC1RAB9AGMNNUSP2LMNA | |
| SCHEMBL25996829 | 0.79 | GPR3 (0.45) | NPC1RAB9AGMNNUSP2LMNA | |
| SCHEMBL8149240 | 0.79 | GAA (0.43) | NPC1RAB9AGMNNUSP2LMNA | |
| SCHEMBL29546263 | 0.77 | NR4A1 (0.56) | NPC1RAB9AGMNNUSP2LMNA | |
| SCHEMBL442684 | 0.77 | NR4A1 (0.56) | NPC1RAB9AGMNNUSP2LMNA | |
| SCHEMBL16955162 | 0.76 | GPR3 (0.42) | NPC1RAB9AGMNNUSP2LMNA | |
| SCHEMBL16953635 | 0.76 | GPR3 (0.42) | NPC1RAB9AGMNNUSP2LMNA | |
| SCHEMBL16958727 | 0.75 | GPR3 (0.45) | NPC1RAB9AGMNNUSP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |