Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | GPR3 | P46089 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SCN4A | P35499 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29546263 | 1.00 | NR4A1 (0.56) | NR4A1GPR3NPC1RAB9AGMNN | |
| Hydrochloric Acid SCHEMBL9526864 | 0.98 | NR4A1 (0.54) | NR4A1GPR3NPC1RAB9AGMNN | |
| SCHEMBL23651402 | 0.88 | NR4A1 (0.65) | NR4A1GPR3NPC1RAB9AGMNN | |
| SCHEMBL24024734 | 0.84 | MEN1 (0.54) | NR4A1GAASCN5ASCN2AMAPK1 | |
| SCHEMBL1275899 | 0.83 | GPR3 (0.46) | GPR3NPC1RAB9AGMNNUSP2 | |
| SCHEMBL30459994 | 0.83 | GPR3 (0.46) | GPR3NPC1RAB9AGMNNUSP2 | |
| SCHEMBL519232 | 0.83 | ALDH1A1 (0.46) | GPR3NPC1RAB9AGMNNUSP2 | |
| SCHEMBL4448251 | 0.82 | MAPT (0.49) | NR4A1LMNATP53CYP3A4GAA | |
| SCHEMBL1351195 | 0.81 | CYP3A4 (0.45) | GPR3NPC1RAB9AGMNNUSP2 | |
| SCHEMBL11832556 | 0.81 | GPR3 (0.44) | NR4A1GPR3NPC1RAB9AGMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 278 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103012171-B | Preparation method of 4-chloro-5(trifluoromethoxy)-1,2-phenylenediamine | BIOCOMPOUNDS PHARMACEUTICAL INC BPI | 2015-07-22 | — | — | CN | claimed |
| JP-2264762-A | — | — | None | — | — | JP | disclosed |
| EP-4559908-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | S2CBio Inc. (KR) | 2025-05-28 | — | — | EP | disclosed |
| WO-2025074873-A1 | POLYAMIDIMIDE, RESIN COMPOSITION, MOLDED ARTICLE, AND FILM | 株式会社カネカ | 2025-04-10 | — | — | WO | disclosed |
| WO-2025063230-A1 | POLYIMIDE, RESIN COMPOSITION, MOLDED OBJECT, AND FILM | 株式会社カネカ | 2025-03-27 | — | — | WO | disclosed |
| CN-119235860-A | N (N)2,N3Application of di-tert-butylquinoxaline-2, 3-diamine derivative in preparation of antitumor pharmaceutical composition | 广西科技大学 | 2025-01-03 | — | — | CN | disclosed |
| US-20240409533-A1 | HMOX1 INDUCERS | Astellas Engineered Small Molecules US, Incorporated | 2024-12-12 | — | — | US | disclosed |
| US-12071433-B2 | HMOX1 inducers | Astellas Engineered Small Molecules US, Incorporated (US) | 2024-08-27 | — | — | US | disclosed |
| US-20240132479-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2024-04-25 | — | — | US | disclosed |
| WO-2024058617-A1 | ANTIVIRAL USE OF HETEROARYL DERIVATIVE COMPOUND | 일동제약(주) | 2024-03-21 | — | — | WO | disclosed |
| US-6127547-A | FOR CROP PROTECTION; SUCH AS 2-BROMO-6,6-DIFLUORO(1,3)DIOXOLO(4,5-F)BENZIMIDAZOLE | BAYER AKTIENGESELLSCHAFT (DE) | 2000-10-03 | — | — | US | disclosed |
| US-6020354-A | FUNGICIDES, BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-02-01 | — | — | US | disclosed |
| EP-0974576-A2 | Method of producing benzamide derivatives | Mitsui Chemicals, Inc. (JP) | 2000-01-26 | — | — | EP | disclosed |
| EP-0844998-A1 | HALOBENZIMIDAZOLES AND THEIR USE AS MICROBICIDES | BAYER AG (DE) | 1998-06-03 | — | — | EP | disclosed |
| WO-1997006171-A1 | HALOBENZIMIDAZOLES AND THEIR USE AS MICROBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-20 | — | — | WO | disclosed |
| EP-0251014-B1 | 2-TRIFLUOROMETHYL BENZIMIDAZOLES | BAYER AG (DE) | 1992-05-20 | — | — | EP | disclosed |
| US-5049574-A | Psychotic diseases | RHONE-POULENC SANTE (FR) | 1991-09-17 | — | — | US | disclosed |
| JP-H02264762-A | 5-TRIFLUOROMETHOXY-2-MBENZIMIDAZOLAMINE, PREPARATION THEREOF AND USE THEREOF | RHONE POULENC SANTE | 1990-10-29 | — | — | JP | disclosed |
| US-4767444-A | Herbicidal and microbiocidal 2-trifluoromethyl-benzimidazoles | BAYER AKTIENGESELLSCHAFT (DE) | 1988-08-30 | — | — | US | disclosed |
| EP-0251014-A2 | 2-Trifluoromethyl benzimidazoles | BAYER AG (DE) | 1988-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240409533-A1 | HMOX1 INDUCERS | HMOX1, HMOX2, HMBS | NR4A1 1284/4885GPR3 4520/4885NPC1 3451/4885 |
| US-12071433-B2 | HMOX1 inducers | HMOX1, HMOX2, HMBS | NR4A1 1157/4885GPR3 4539/4885NPC1 3292/4885 |
| US-20240132479-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | CUTA, DCXR, PLOD3 | NR4A1 4576/4885GPR3 4545/4885NPC1 4876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.