Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31422953 | 0.83 | DAO (0.35) | ALDH1A1KDM4EKMT2AMEN1TSHR | |
| SCHEMBL31423104 | 0.82 | KDM4E (0.42) | ALDH1A1KDM4ETSHRHSD17B10MAOB | |
| SCHEMBL31423089 | 0.82 | MAOB (0.51) | ALDH1A1KDM4EKMT2AMEN1TSHR | |
| SCHEMBL31422768 | 0.81 | MAOB (0.53) | ALDH1A1KDM4EKMT2AMEN1TSHR | |
| SCHEMBL31229604 | 0.79 | MAOB (0.46) | ALDH1A1KDM4EKMT2AMEN1TSHR | |
| SCHEMBL19512086 | 0.76 | ALDH1A1 (0.55) | ALDH1A1KDM4EKMT2AMEN1TSHR | |
| SCHEMBL6161066 | 0.76 | ALOX15 (0.69) | ALDH1A1KDM4EKMT2AMEN1TSHR | |
| SCHEMBL30237524 | 0.76 | ALDH1A1 (0.55) | ALDH1A1KDM4EKMT2AMEN1TSHR | |
| SCHEMBL5114852 | 0.75 | KDM4E (0.53) | ALDH1A1KDM4EKMT2AMEN1TSHR | |
| SCHEMBL31423182 | 0.75 | KDM4E (0.53) | ALDH1A1KDM4EKMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |