Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31423089 | 0.90 | MAOB (0.51) | MAOBMAOAALDH1A1LMNAL3MBTL1 | |
| SCHEMBL31422768 | 0.89 | MAOB (0.53) | MAOBMAOAALDH1A1LMNAL3MBTL1 | |
| SCHEMBL31423110 | 0.88 | KDM4E (0.40) | ALDH1A1LMNAL3MBTL1KDM4EHSD17B10 | |
| SCHEMBL31423294 | 0.83 | TBK1 (0.45) | MAOBALDH1A1KDM4EGAAPOLB | |
| SCHEMBL31423253 | 0.79 | ALDH1A1 (0.47) | MAOBMAOAALDH1A1LMNAL3MBTL1 | |
| SCHEMBL29479161 | 0.79 | KDM4E (0.44) | ALDH1A1L3MBTL1KDM4EHSD17B10TSHR | |
| SCHEMBL27096449 | 0.79 | KDM4E (0.44) | ALDH1A1L3MBTL1KDM4EHSD17B10TSHR | |
| SCHEMBL31273396 | 0.77 | KDM4E (0.42) | ALDH1A1LMNAL3MBTL1KDM4EHSD17B10 | |
| SCHEMBL21354823 | 0.77 | ALOX15 (0.64) | ALDH1A1LMNAL3MBTL1MAPTKDM4E | |
| SCHEMBL23732403 | 0.76 | RAB9A (0.60) | MAOBMAOAALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024222866-A1 | CYCLIC DERIVATIVES, COMPOSITIONS AND USES THEREOF | DANATLAS PHARMACEUTICALS CO., LTD. (CN) | 2024-10-31 | — | — | WO | disclosed |