Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | DAO | P14920 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | DDO | Q99489 | 2/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31423253 | 0.82 | ALDH1A1 (0.47) | KDM4EALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL31422953 | 0.81 | DAO (0.35) | KDM4EALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL31273139 | 0.81 | KDM4E (0.46) | KDM4EALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL31423285 | 0.78 | ACMSD (0.52) | KDM4EALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL31273616 | 0.78 | ACMSD (0.49) | KDM4EALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL31423183 | 0.77 | ACMSD (0.54) | KDM4EALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL31423294 | 0.75 | TBK1 (0.45) | KDM4EALDH1A1GAAPOLBSMYD3 | |
| SCHEMBL31423389 | 0.75 | KDM4E (0.43) | KDM4EALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL31423115 | 0.74 | DAO (0.63) | KDM4EALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL2807085 | 0.72 | CASP3 (0.55) | KDM4EALDH1A1GAAPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |