Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.66 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.62 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.62 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.50 |
| ▸ | CCR1 | P32246 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30025133 | 1.00 | PLK1 (0.66) | PLK1TAS1R3TAS1R1ADORA2AALOX15 | |
| SCHEMBL4986392 | 0.87 | PLK1 (0.63) | PLK1TAS1R3TAS1R1ALOX15HTT | |
| SCHEMBL30024398 | 0.85 | PLK1 (0.47) | PLK1TAS1R3TAS1R1ADORA2AALOX15 | |
| SCHEMBL5006955 | 0.82 | CLK1 (0.62) | PLK1TAS1R3TAS1R1ALOX15HTT | |
| SCHEMBL26697800 | 0.80 | PLK1 (0.54) | PLK1TAS1R3TAS1R1ALOX15HTT | |
| SCHEMBL5007649 | 0.80 | ROCK2 (0.63) | TAS1R3TAS1R1 | |
| SCHEMBL11962154 | 0.80 | PLK1 (1.00) | PLK1TAS1R3TAS1R1ALOX15HTT | |
| SCHEMBL703553 | 0.79 | PLK1 (0.63) | PLK1TAS1R3TAS1R1ALOX15HTT | |
| SCHEMBL7464595 | 0.79 | TAS1R3 (0.69) | PLK1TAS1R3TAS1R1ALOX15HTT | |
| SCHEMBL10273916 | 0.79 | TAS1R3 (0.69) | PLK1TAS1R3TAS1R1ALOX15HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119552151-B | PRMT5 inhibitors and uses thereof | 赛岚(杭州)生物医药科技有限公司 | 2025-05-02 | — | — | CN | disclosed |
| CN-119552151-A | Novel PRMT5 inhibitors and uses thereof | 赛岚(杭州)生物医药科技有限公司 | 2025-03-04 | — | — | CN | disclosed |