SCHEMBL3142935

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16846211	0.89	HTT (0.55)	MEN1KMT2APOLBKDM1AHTT
	SCHEMBL16826180	0.89	HTT (0.55)	MEN1KMT2APOLBKDM1AHTT
	SCHEMBL7130405	0.86	HDAC8 (0.54)	MEN1KMT2APOLBKDM1AHTT
	SCHEMBL4156092	0.79	VEGFA (0.58)	MEN1KMT2AKDM1AHTTESR2
	SCHEMBL16825770	0.77	KDM1A (0.48)	MEN1KMT2APOLBKDM1AHTT
	SCHEMBL4681343	0.76	KDM1A (0.56)	MEN1KMT2AKDM1AESR2LMNA
	SCHEMBL4685294	0.76	KDM1A (0.56)	MEN1KMT2AKDM1AESR2SMN1; SMN2
	SCHEMBL2850833	0.76	KDM1A (0.48)	MEN1KMT2APOLBKDM1AESR2
	SCHEMBL9489224	0.76	P2RX7 (0.72)	KMT2AP2RX7
	SCHEMBL9489228	0.76	P2RX7 (0.72)	KMT2AP2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.