Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27040982 | 0.84 | ALDH1A1 (0.48) | ALDH1A1ALOX15MAOAMAOBHPGD | |
| SCHEMBL24436718 | 0.83 | THRB (0.42) | ALDH1A1P2RX1MAOAMAOBCA12 | |
| SCHEMBL27630883 | 0.83 | ALDH1A1 (0.42) | ALDH1A1ALOX15P2RX1KDM4ETSHR | |
| SCHEMBL24445844 | 0.80 | LMNA (0.56) | ALDH1A1P2RX1KDM4ECA12CA1 | |
| SCHEMBL27675720 | 0.79 | MAPT (0.40) | ALDH1A1ALOX15P2RX1MAOAMAOB | |
| SCHEMBL16961273 | 0.79 | MEN1 (0.34) | ALDH1A1ALOX15P2RX1MAOAMAOB | |
| SCHEMBL28089519 | 0.76 | KLK1 (0.37) | ALDH1A1P2RX1MAOAMAOBHPGD | |
| SCHEMBL2091798 | 0.74 | TSHR (0.45) | ALDH1A1ALOX15P2RX1HPGDCA1 | |
| SCHEMBL249223 | 0.73 | KCNK3 (0.49) | ALDH1A1ALOX15KCNK3KCNK9 | |
| SCHEMBL1793852 | 0.72 | ALDH1A1 (0.44) | ALDH1A1ALOX15KCNK3KCNK9P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119350422-B | Deubiquitinase targeting chimeric compound and preparation method and application thereof | 中国药科大学 | 2025-04-04 | — | — | CN | disclosed |
| CN-119350422-A | Deubiquitinase targeting chimeric compound and preparation method and application thereof | 中国药科大学 | 2025-01-24 | — | — | CN | disclosed |