Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 5/20 | 0.32 |
| ▸ | CA12 | O43570 | 4/20 | 0.32 |
| ▸ | CA1 | P00915 | 4/20 | 0.32 |
| ▸ | CA2 | P00918 | 4/20 | 0.32 |
| ▸ | CA9 | Q16790 | 4/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 2/20 | 0.31 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20635363 | 0.77 | DGAT1 (0.43) | DGAT1GAAEPHX1HPGDSSTR4 | |
| SCHEMBL28077248 | 0.75 | DGAT1 (0.45) | DGAT1GAAEPHX1HPGDSSTR4 | |
| SCHEMBL27950403 | 0.74 | GAA (0.41) | DGAT1GAAEPHX1HPGDSSTR4 | |
| SCHEMBL28201093 | 0.73 | DGAT1 (0.39) | DGAT1GAAEPHX1HPGDSSTR4 | |
| SCHEMBL6597535 | 0.72 | DGAT1 (0.42) | DGAT1GAAEPHX1HPGDSSTR4 | |
| SCHEMBL28077255 | 0.71 | EPHX1 (0.39) | DGAT1GAAEPHX1HPGDCHRM2 | |
| SCHEMBL27843694 | 0.71 | CTSS (0.36) | DGAT1GAAEPHX1HPGDBTK | |
| SCHEMBL6512299 | 0.70 | DGAT1 (0.41) | DGAT1GAAEPHX1HPGDBTK | |
| SCHEMBL1372061 | 0.70 | DGAT1 (0.46) | DGAT1GAAEPHX1HPGDCA12 | |
| SCHEMBL26605075 | 0.70 | DGAT1 (0.37) | DGAT1GAAEPHX1HPGDSSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119350422-B | Deubiquitinase targeting chimeric compound and preparation method and application thereof | 中国药科大学 | 2025-04-04 | — | — | CN | disclosed |
| CN-119350422-A | Deubiquitinase targeting chimeric compound and preparation method and application thereof | 中国药科大学 | 2025-01-24 | — | — | CN | disclosed |