Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8974165 | 0.87 | NPC1 (0.53) | RAB9ANPC1KMT2AMEN1APP | |
| SCHEMBL27617094 | 0.85 | RAB9A (0.56) | RAB9ANPC1KMT2AMEN1APP | |
| SCHEMBL3135082 | 0.82 | KEAP1 (0.51) | RAB9ANPC1KMT2AMEN1APP | |
| SCHEMBL7035834 | 0.82 | ACHE (0.57) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL5528929 | 0.79 | MAPT (0.70) | RAB9ANPC1KMT2AMEN1APP | |
| SCHEMBL6510195 | 0.79 | MAPT (0.54) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL8702382 | 0.79 | MEN1 (0.56) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL7035833 | 0.79 | NPC1 (0.46) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL22164075 | 0.79 | ELANE (0.48) | RAB9ANPC1MAPTCYP1A2LMNA | |
| SCHEMBL28596462 | 0.79 | ALDH1A1 (0.57) | RAB9ANPC1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100000606-A1 | ORGANIC PHOTOSENSITIVE DEVICES | THOMPSON MARK E | 2010-01-07 | — | — | US | disclosed |
| EP-1728285-A1 | HEAVY METAL COMPLEXES FOR ORGANIC PHOTOSENSITIVE DEVICES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005098990-A1 | HEAVY METAL COMPLEXES FOR ORGANIC PHOTOSENSITIVE DEVICES | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2005-10-20 | — | — | WO | disclosed |
| US-20050211974-A1 | Organic photosensitive devices | UNIVERSITY OF SOUTHERN CALIFORNIA, THE | 2005-09-29 | — | — | US | disclosed |