Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31431925 | 0.86 | FFAR4 (0.57) | ALDH1A1HPGDLMNAKDM4EMEN1 | |
| SCHEMBL3279892 | 0.77 | LMNA (0.59) | POLBALDH1A1HPGDLMNAL3MBTL1 | |
| SCHEMBL7594450 | 0.76 | CA2 (0.58) | POLBALDH1A1HPGDLMNAL3MBTL1 | |
| SCHEMBL15359721 | 0.76 | POLB (0.49) | POLBALDH1A1HPGDLMNAL3MBTL1 | |
| SCHEMBL3983832 | 0.74 | HPGD (0.65) | POLBALDH1A1HPGDLMNAL3MBTL1 | |
| SCHEMBL15830076 | 0.74 | POLB (0.63) | POLBALDH1A1HPGDLMNAL3MBTL1 | |
| SCHEMBL527397 | 0.72 | ALDH1A1 (0.52) | POLBALDH1A1LMNAL3MBTL1KDM4E | |
| SCHEMBL2721981 | 0.72 | ALDH1A1 (0.49) | POLBALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL1026910 | 0.70 | HTT (0.49) | POLBALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL5713274 | 0.70 | ALDH1A1 (0.52) | POLBALDH1A1LMNAL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049326-A1 | TRICYCLIC HETEROAROMATIC INHIBITORS OF KLK5 | BIOCRYST PHARMACEUTICALS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |