Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.33 |
| ▸ | LPL | P06858 | 2/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31431212 | 0.88 | SMYD2 (0.34) | SMYD2LPLLIPG | |
| SCHEMBL31431189 | 0.76 | ADRA1D (0.35) | SMYD2 | |
| SCHEMBL15967484 | 0.75 | LPL (0.31) | SMYD2LPLLIPGDGAT1 | |
| SCHEMBL20972246 | 0.73 | LIPE (0.36) | — | |
| SCHEMBL17012560 | 0.73 | LIPE (0.34) | — | |
| SCHEMBL4116949 | 0.73 | SMYD2 (0.31) | SMYD2 | |
| SCHEMBL7594780 | 0.72 | KDM4E (0.32) | — | |
| SCHEMBL1180716 | 0.72 | DGAT1 (0.48) | LPLLIPGDGAT1 | |
| SCHEMBL31431866 | 0.72 | SMYD2 (0.34) | SMYD2LPLLIPG | |
| SCHEMBL4368089 | 0.72 | CYP3A4 (0.30) | SMYD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049326-A1 | TRICYCLIC HETEROAROMATIC INHIBITORS OF KLK5 | BIOCRYST PHARMACEUTICALS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |