SCHEMBL31432460

SCHEMBL31432460

C=COc1cc(OC)ccc1C=O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.71
TRIM24 O15164 1/20 0.54
TYR P14679 1/20 0.54
TRIM33 Q9UPN9 1/20 0.54
CYP1A2 P05177 10/20 0.50
CYP1A1 P04798 7/20 0.50
CYP1B1 Q16678 7/20 0.50
ERN1 O75460 2/20 0.50
CYP2C19 P33261 4/20 0.47
CYP2C9 P11712 2/20 0.47
LMNA P02545 1/20 0.47
MAPT P10636 3/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
NFE2L2 Q16236 2/20 0.45
KDM4E B2RXH2 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
GAA P10253 1/20 0.43
CYP3A4 P08684 2/20 0.42
CYP2E1 P05181 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL4914414 0.84 ALDH1A1 (0.92) ALDH1A1TRIM24TYRTRIM33CYP1A2
Formaldehyde SCHEMBL28854145 0.84 ALDH1A1 (0.92) ALDH1A1TRIM24TYRTRIM33CYP1A2
SCHEMBL96291 0.83 ALDH1A1 (1.00) ALDH1A1TRIM24TYRTRIM33CYP1A2
Hydrochloric Acid SCHEMBL9456784 0.82 ALDH1A1 (0.96) ALDH1A1TRIM24TYRTRIM33CYP1A2
SCHEMBL899151 0.79 ALDH1A1 (0.71) ALDH1A1TRIM24TYRTRIM33CYP1A2
SCHEMBL3340189 0.79 ALDH1A1 (0.65) ALDH1A1TRIM24TYRTRIM33CYP1A2
SCHEMBL16381877 0.79 ALDH1A1 (0.76) ALDH1A1TRIM24TYRTRIM33CYP1A2
SCHEMBL13168673 0.78 ALDH1A1 (0.69) ALDH1A1TRIM24TYRTRIM33CYP1A2
SCHEMBL16111393 0.77 ALDH1A1 (0.73) ALDH1A1TRIM24TYRTRIM33CYP1A2
SCHEMBL10861186 0.77 ALDH1A1 (0.61) ALDH1A1TRIM24TYRTRIM33CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4741389-A1 KAT6 INHIBITOR Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. (CN) 2026-05-13 EP disclosed
WO-2025007873-A1 KAT6 INHIBITOR 上海齐鲁制药研究中心有限公司 2025-01-09 WO disclosed