Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.57 |
| ▸ | TYR | P14679 | 1/20 | 0.57 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.57 |
| ▸ | ERN1 | O75460 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9055047 | 0.85 | ALDH1A1 (0.71) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL16111393 | 0.83 | ALDH1A1 (0.73) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| Formaldehyde SCHEMBL28854145 | 0.82 | ALDH1A1 (0.92) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| Ethylene SCHEMBL4914414 | 0.82 | ALDH1A1 (0.92) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL96291 | 0.82 | ALDH1A1 (1.00) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL16046208 | 0.81 | ALDH1A1 (0.71) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| Hydrochloric Acid SCHEMBL9456784 | 0.80 | ALDH1A1 (0.96) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL31432460 | 0.78 | ALDH1A1 (0.71) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL6131805 | 0.78 | ALDH1A1 (0.65) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL9055043 | 0.78 | ALDH1A1 (0.65) | ALDH1A1TRIM24TYRTRIM33ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247439-A1 | DENDRITIC NANO-ANTIOXIDANTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100247439-A1 | DENDRITIC NANO-ANTIOXIDANTS | GPX1, GPX4, LPO | ALDH1A1 235/4885TRIM24 4576/4885TYR 34/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.