SCHEMBL31433160

SCHEMBL31433160

Cc1ccc(-c2ncno2)cn1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGDS O60760 1/20 0.41
ELANE P08246 1/20 0.40
TDO2 P48775 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
PKM P14618 1/20 0.36
PIK3CA P42336 3/20 0.34
PIK3CD O00329 1/20 0.34
PIK3CB P42338 1/20 0.34
PI4KA P42356 1/20 0.34
PIK3CG P48736 1/20 0.34
PI4KB Q9UBF8 1/20 0.34
ALOX5AP P20292 1/20 0.34
PTGS2 P35354 2/20 0.33
MTOR P42345 2/20 0.33
GABRA1 P14867 2/20 0.33
MAPK1 P28482 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2E1 P05181 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12489671 1.00 HPGDS (0.41) HPGDSELANETDO2ADORA3NPC1
SCHEMBL6848071 0.78 NPC1 (0.44) NPC1RAB9APKM
SCHEMBL24921577 0.77 CA1 (0.47) TDO2PIK3CAPIK3CDPIK3CBPI4KA
SCHEMBL14804388 0.74 NPC1 (0.53) HPGDSELANENPC1RAB9APKM
SCHEMBL676678 0.73 HPGDS (0.56) HPGDSELANETDO2NPC1RAB9A
SCHEMBL255920 0.73 CHRNB2 (0.53) TDO2NPC1RAB9APKMCYP1A2
SCHEMBL12490255 0.72 ACHE (0.58) HPGDSELANEADORA3NPC1RAB9A
SCHEMBL17051516 0.71 HPGDS (0.54) HPGDSELANETDO2NPC1RAB9A
SCHEMBL17656019 0.69 NPC1 (0.50) TDO2NPC1RAB9AATM
SCHEMBL1186813 0.69 ESR1 (0.42) NPC1RAB9APKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025052333-A1 NOVEL 1,2,4-OXADIAZOLES COMPOUNDS AS FUNGICIDE PI INDUSTRIES LTD. (IN) 2025-03-13 WO disclosed