Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 6/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 6/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 4/20 | 0.38 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31434048 | 0.92 | GPR119 (0.35) | GRM5GRM1PDK4GPR119CDK9 | |
| SCHEMBL26924679 | 0.91 | GRM5 (0.41) | GRM5GRM1PDK4GPR119TNK2 | |
| SCHEMBL30731864 | 0.91 | GRM5 (0.41) | GRM5GRM1PDK4GPR119TNK2 | |
| SCHEMBL31433805 | 0.90 | YAP1 (0.36) | GPR119CDK9CCNT1TLR9TLR7 | |
| SCHEMBL31433920 | 0.90 | GPR119 (0.35) | GPR119CDK9TNFCCNT1TLR9 | |
| SCHEMBL31433974 | 0.90 | GPR119 (0.35) | GPR119CDK9TNFCCNT1TLR9 | |
| SCHEMBL31433941 | 0.90 | GPR119 (0.35) | GPR119CDK9TNFCCNT1TLR9 | |
| SCHEMBL31433646 | 0.88 | GPR119 (0.33) | GRM5GRM1GPR119CDK9PDE10A | |
| SCHEMBL31433745 | 0.88 | GPR119 (0.33) | GRM5GRM1GPR119CDK9PDE10A | |
| SCHEMBL30732152 | 0.88 | TNF (0.44) | GRM5GRM1PDK4GPR119CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049964-A1 | BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-03-06 | — | — | WO | disclosed |
| WO-2025050016-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-03-06 | — | — | WO | disclosed |