Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.35 |
| ▸ | YAP1 | P46937 | 3/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31433920 | 1.00 | GPR119 (0.35) | GPR119YAP1PRMT5TLR9TLR7 | |
| SCHEMBL31433974 | 1.00 | GPR119 (0.35) | GPR119YAP1PRMT5TLR9TLR7 | |
| SCHEMBL31433587 | 0.90 | GRM5 (0.39) | GPR119TLR9TLR7CCNT1CCNA2 | |
| SCHEMBL31434035 | 0.89 | TNF (0.38) | GPR119YAP1PRMT5TLR9TLR7 | |
| SCHEMBL31433805 | 0.89 | YAP1 (0.36) | GPR119YAP1PRMT5TLR9TLR7 | |
| SCHEMBL31434048 | 0.87 | GPR119 (0.35) | GPR119PRMT5TLR9TLR7CDK9 | |
| SCHEMBL30732121 | 0.86 | PRMT5 (0.38) | GPR119YAP1PRMT5TLR9TLR7 | |
| SCHEMBL30732110 | 0.86 | PRMT5 (0.38) | GPR119YAP1PRMT5TLR9TLR7 | |
| SCHEMBL30731978 | 0.86 | PRMT5 (0.38) | GPR119YAP1PRMT5TLR9TLR7 | |
| SCHEMBL26924596 | 0.86 | PRMT5 (0.38) | GPR119YAP1PRMT5TLR9TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025050016-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-03-06 | — | — | WO | disclosed |