Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.31 |
| ▸ | YAP1 | P46937 | 1/20 | 0.31 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31433811 | 1.00 | TNF (0.36) | TNFBTKGPR119ALOX5APFEN1 | |
| SCHEMBL31433692 | 1.00 | TNF (0.36) | TNFBTKGPR119ALOX5APFEN1 | |
| SCHEMBL31433618 | 0.95 | TNF (0.37) | TNFBTKGPR119ALOX5APFEN1 | |
| SCHEMBL31433651 | 0.95 | TNF (0.37) | TNFBTKGPR119ALOX5APFEN1 | |
| SCHEMBL30732188 | 0.91 | GPR119 (0.37) | BTKGPR119DGAT2PRMT5TLR9 | |
| SCHEMBL30731912 | 0.91 | GPR119 (0.37) | BTKGPR119DGAT2PRMT5TLR9 | |
| SCHEMBL30731817 | 0.91 | GPR119 (0.37) | BTKGPR119DGAT2PRMT5TLR9 | |
| SCHEMBL31433550 | 0.90 | DGAT2 (0.33) | BTKGPR119CCNT1CDK9DGAT2 | |
| SCHEMBL31433808 | 0.90 | DGAT2 (0.33) | BTKGPR119CCNT1CDK9DGAT2 | |
| SCHEMBL31433520 | 0.90 | DGAT2 (0.33) | BTKGPR119CCNT1CDK9DGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049964-A1 | BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-03-06 | — | — | WO | disclosed |
| WO-2025050016-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-03-06 | — | — | WO | disclosed |