Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.32 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.32 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.32 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.32 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.32 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.32 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 4/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 4/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CCR3 | P51677 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31433520 | 1.00 | DGAT2 (0.33) | DGAT2GPR119CCNT1CDK9PRMT5 | |
| SCHEMBL31433550 | 1.00 | DGAT2 (0.33) | DGAT2GPR119CCNT1CDK9PRMT5 | |
| SCHEMBL31433844 | 0.95 | CCNT1 (0.34) | DGAT2GPR119CCNT1CDK9PRMT5 | |
| SCHEMBL31433862 | 0.95 | CCNT1 (0.34) | DGAT2GPR119CCNT1CDK9PRMT5 | |
| SCHEMBL31433646 | 0.92 | GPR119 (0.33) | DGAT2GPR119CCNT1CDK9PRMT5 | |
| SCHEMBL31433745 | 0.92 | GPR119 (0.33) | DGAT2GPR119CCNT1CDK9PRMT5 | |
| SCHEMBL26925201 | 0.91 | LMNA (0.36) | GPR119CCNT1CDK9PRMT5PRKAB2 | |
| SCHEMBL30732082 | 0.91 | LMNA (0.36) | GPR119CCNT1CDK9PRMT5PRKAB2 | |
| SCHEMBL31433657 | 0.90 | TNF (0.36) | DGAT2GPR119CCNT1CDK9PRMT5 | |
| SCHEMBL31433692 | 0.90 | TNF (0.36) | DGAT2GPR119CCNT1CDK9PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049964-A1 | BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-03-06 | — | — | WO | disclosed |
| WO-2025050016-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-03-06 | — | — | WO | disclosed |