Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8354088 | 0.92 | SMYD2 (0.36) | SMYD2CYP3A4HTTSMN1; SMN2CYP2C19 | |
| SCHEMBL26566724 | 0.87 | CYP3A4 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2CYP2C19 | |
| SCHEMBL10828679 | 0.85 | SMYD2 (0.35) | SMYD2CYP3A4HTTSMN1; SMN2CYP2C19 | |
| Hydrochloric Acid SCHEMBL29015997 | 0.85 | ALOX15 (0.41) | SMYD2CYP3A4HTTSMN1; SMN2CYP2C19 | |
| SCHEMBL789538 | 0.85 | ALOX15 (0.41) | SMYD2CYP3A4HTTSMN1; SMN2CYP2C19 | |
| SCHEMBL8199953 | 0.84 | CES2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2MAPT | |
| SCHEMBL7336991 | 0.83 | SMYD2 (0.38) | SMYD2CYP3A4HTTSMN1; SMN2CYP2C19 | |
| SCHEMBL4810133 | 0.82 | SMYD2 (0.35) | SMYD2CYP3A4HTTSMN1; SMN2CYP2C19 | |
| SCHEMBL25712841 | 0.82 | KDM4E (0.39) | SMYD2CYP3A4HTTSMN1; SMN2MAPT | |
| SCHEMBL16436931 | 0.82 | MCL1 (0.35) | SMYD2CYP3A4HTTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331670-A1 | GLYCEROL COMPOUNDS AND METHODS OF USE | ENZYCHEM LIFESCIENCES CORP (KR) | 2023-10-19 | — | — | US | disclosed |
| EP-3042900-B1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORP (JP) | 2020-09-23 | — | — | EP | disclosed |
| US-9586951-B2 | Morpholine derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2017-03-07 | — | — | US | disclosed |
| US-9586951-B2 | Morpholine derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2017-03-07 | — | — | US | disclosed |
| EP-3042900-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | Fujifilm Corporation (JP) | 2016-07-13 | — | — | EP | disclosed |
| EP-3042900-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | Fujifilm Corporation (JP) | 2016-07-13 | — | — | EP | disclosed |
| US-20160168139-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2016-06-16 | — | — | US | disclosed |
| US-20160168139-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2016-06-16 | — | — | US | disclosed |
| WO-2015030057-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | 富士フイルム株式会社 (JP) | 2015-03-05 | — | — | WO | disclosed |
| US-5874464-A | ANTAGONIST OF PROTEIN KINASE C | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1999-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168139-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | PRMT7, RBBP7, RER1 | SMYD2 718/4885CYP3A4 3441/4885HTT 3547/4885 |
| US-20230331670-A1 | GLYCEROL COMPOUNDS AND METHODS OF USE | GK, MGLL, DGAT2 | SMYD2 1807/4885CYP3A4 1716/4885HTT 1059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.