Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 3/20 | 0.37 |
| ▸ | CLK2 | P49760 | 3/20 | 0.37 |
| ▸ | HIPK1 | Q86Z02 | 3/20 | 0.37 |
| ▸ | HIPK2 | Q9H2X6 | 3/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.37 |
| ▸ | HIPK3 | Q9H422 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31434710 | 0.86 | CLK2 (0.43) | CLK1CLK2HIPK1HIPK2CLK4 | |
| SCHEMBL31434740 | 0.83 | CYP1A2 (0.36) | CYP1A2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL31434665 | 0.81 | CYP1A2 (0.41) | RAB9ACYP1A2GABRA1GABRG2GABRB3 | |
| SCHEMBL31434828 | 0.80 | RAB9A (0.38) | NPC1RAB9ACYP1A2IDO1GABRA1 | |
| SCHEMBL31434695 | 0.80 | IDO1 (0.36) | NPC1RAB9ASMN1; SMN2CYP1A2IDO1 | |
| SCHEMBL31434623 | 0.79 | CYP1A2 (0.40) | NPC1RAB9ACYP1A2GABRA1GABRG2 | |
| SCHEMBL754523 | 0.75 | ALDH1A1 (0.46) | NPC1RAB9ASMN1; SMN2CYP1A2GABRA2 | |
| SCHEMBL14811073 | 0.75 | NAMPT (0.47) | NPC1RAB9ASMN1; SMN2CYP1A2CDC7 | |
| SCHEMBL11564835 | 0.75 | CYP1A2 (0.50) | NPC1RAB9ASMN1; SMN2CYP1A2GABRA2 | |
| SCHEMBL31434721 | 0.73 | CACNA1G (0.38) | SMN1; SMN2CYP1A2GABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085347-A1 | IL4I1 INHIBITORS AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2025-04-24 | — | — | WO | disclosed |