Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 7/20 | 0.35 |
| ▸ | DBF4 | Q9UBU7 | 7/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31434788 | 0.85 | ECE1 (0.38) | RAB9ANPC1TLR7CACNA1GCACNA1H | |
| SCHEMBL31434853 | 0.84 | MAPT (0.38) | RAB9AMAPTNPC1POLBPKM | |
| SCHEMBL31434695 | 0.82 | IDO1 (0.36) | RAB9AMAPTNPC1CYP1A2CDC7 | |
| SCHEMBL31434665 | 0.82 | CYP1A2 (0.41) | RAB9AMAPTPOLBCYP1A2GAA | |
| SCHEMBL31434652 | 0.80 | CLK1 (0.37) | RAB9AMAPTNPC1CYP1A2CDC7 | |
| SCHEMBL31434623 | 0.78 | CYP1A2 (0.40) | RAB9AMAPTNPC1POLBCYP1A2 | |
| SCHEMBL754523 | 0.73 | ALDH1A1 (0.46) | RAB9AMAPTNPC1POLBNPSR1 | |
| SCHEMBL11564835 | 0.73 | CYP1A2 (0.50) | RAB9AMAPTNPC1NPSR1LMNA | |
| SCHEMBL31434721 | 0.71 | CACNA1G (0.38) | MAPTPOLBCYP1A2KDM4EALDH1A1 | |
| SCHEMBL30363842 | 0.71 | CYP1A2 (0.59) | RAB9AMAPTNPC1POLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085347-A1 | IL4I1 INHIBITORS AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2025-04-24 | — | — | WO | disclosed |