Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31434857 | 0.84 | CES1 (0.40) | ALDH1A1HPGD | |
| SCHEMBL11564835 | 0.81 | CYP1A2 (0.50) | MAPTSMN1; SMN2ALDH1A1LMNAGABRA2 | |
| SCHEMBL31434793 | 0.81 | NPC1 (0.46) | MAPTSMN1; SMN2ALDH1A1LMNAGABRA2 | |
| SCHEMBL31434705 | 0.78 | GABRA2 (0.41) | MAPTSMN1; SMN2ALDH1A1LMNAGABRA2 | |
| SCHEMBL31434772 | 0.76 | PPARA (0.47) | MAPTSMN1; SMN2ALDH1A1GABRA2GABRB2 | |
| SCHEMBL31434637 | 0.76 | CDC7 (0.47) | MAPTSMN1; SMN2ALDH1A1LMNAGABRA2 | |
| SCHEMBL31434576 | 0.76 | MAPT (0.51) | MAPTSMN1; SMN2GABRA2GABRB2MAPK1 | |
| SCHEMBL31434754 | 0.76 | GABRA2 (0.45) | MAPTSMN1; SMN2ALDH1A1GABRA2GABRB2 | |
| SCHEMBL31434600 | 0.76 | CYP1A2 (0.40) | MAPTSMN1; SMN2ALDH1A1LMNAGABRA2 | |
| SCHEMBL2792417 | 0.76 | ALDH1A1 (0.59) | MAPTSMN1; SMN2ALDH1A1LMNAGABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085347-A1 | IL4I1 INHIBITORS AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2025-04-24 | — | — | WO | disclosed |