Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 4/20 | 0.35 |
| ▸ | DBF4 | Q9UBU7 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31434798 | 0.85 | ECE1 (0.38) | RAB9AIL4I1ADORA2AADORA1HPGD | |
| SCHEMBL31434828 | 0.84 | RAB9A (0.38) | MAPTNPC1RAB9APOLBPKM | |
| SCHEMBL31434561 | 0.82 | LMNA (0.46) | MAPTNPC1RAB9APOLBPKM | |
| SCHEMBL31434723 | 0.78 | GABRA2 (0.44) | MAPTNPC1RAB9APKMNPSR1 | |
| SCHEMBL31434610 | 0.77 | CYP1A2 (0.41) | MAPTNPC1RAB9APOLBLMNA | |
| SCHEMBL31434683 | 0.75 | HCRTR2 (0.41) | MAPTNPC1RAB9APOLBRXFP1 | |
| SCHEMBL31434700 | 0.73 | CYP1A2 (0.37) | MAPTNPC1RAB9APOLBNPSR1 | |
| SCHEMBL30363842 | 0.71 | CYP1A2 (0.59) | MAPTNPC1RAB9APOLBPKM | |
| SCHEMBL31434600 | 0.71 | CYP1A2 (0.40) | MAPTNPC1RAB9ALMNACYP1A2 | |
| SCHEMBL31434793 | 0.71 | NPC1 (0.46) | MAPTNPC1RAB9APOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085347-A1 | IL4I1 INHIBITORS AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2025-04-24 | — | — | WO | disclosed |