Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 3/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.57 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | ADK | P55263 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | BCR | P11274 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28419565 | 0.89 | KEAP1 (0.57) | KEAP1NFE2L2PLK1ABCG2NPC1 | |
| SCHEMBL3133571 | 0.84 | APP (0.51) | KEAP1NFE2L2NPC1RAB9AMAPT | |
| SCHEMBL3135082 | 0.81 | KEAP1 (0.51) | KEAP1NFE2L2ABCG2NPC1RAB9A | |
| SCHEMBL7232176 | 0.78 | ALDH1A1 (0.57) | KEAP1NFE2L2PLK1NPC1RAB9A | |
| SCHEMBL30780918 | 0.77 | TSHR (0.61) | KEAP1NFE2L2ABCG2NPC1RAB9A | |
| SCHEMBL1413129 | 0.77 | TSHR (0.61) | KEAP1NFE2L2ABCG2NPC1RAB9A | |
| SCHEMBL7237866 | 0.75 | MAPT (0.59) | KEAP1NFE2L2PLK1NPC1RAB9A | |
| SCHEMBL30469276 | 0.75 | MAPT (0.59) | KEAP1NFE2L2PLK1NPC1RAB9A | |
| SCHEMBL19134427 | 0.75 | ASIC3 (0.59) | ABL1BCR | |
| SCHEMBL546381 | 0.75 | ABL1 (0.59) | RAB9ABCHEACHEMAPTPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100000606-A1 | ORGANIC PHOTOSENSITIVE DEVICES | THOMPSON MARK E | 2010-01-07 | — | — | US | disclosed |
| US-20100000606-A1 | ORGANIC PHOTOSENSITIVE DEVICES | THOMPSON MARK E | 2010-01-07 | — | — | US | disclosed |
| EP-1728285-A1 | HEAVY METAL COMPLEXES FOR ORGANIC PHOTOSENSITIVE DEVICES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005098990-A1 | HEAVY METAL COMPLEXES FOR ORGANIC PHOTOSENSITIVE DEVICES | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2005-10-20 | — | — | WO | disclosed |
| US-20050211974-A1 | Organic photosensitive devices | UNIVERSITY OF SOUTHERN CALIFORNIA, THE | 2005-09-29 | — | — | US | disclosed |